Possible key to COVID-19 infectivity
by Sarah Glass
While mutations are often associated with causing diseases such as cancer, Xingyi Guo, PhD, and colleagues have discovered genetic alterations that might reduce infectivity by SARS-CoV-2, the virus that causes COVID-19.
Their work details genetic variations in the ACE2 cell surface receptor that binds to the viral spike (S) protein, how these mutations might destabilize the receptor,...